The video records an ISTDP therapy session with client Kyle, who has been suffering from depression and taking medication since the age of 9 and is struggling with the possibility of having to take medication for the rest of his life. The therapist discusses with Kyle the origins of his depression, his most recent relapse, and his pattern of tending to deal with problems on his own rather than relying on others, and how this pattern affects him.

The speaker shared his own experience of receiving psychotherapy, emphasizing that psychotherapy helps to understand oneself and improve interpersonal relationships. Although the process is not easy, it is very worthwhile. He also called on everyone to pay attention to psychotherapy and regard it as a way to improve themselves, rather than waiting until problems arise.

The video content is a group psychotherapy session for inpatients, discussing Sonia's sadness about her friend leaving, George's feelings for Sonia and what he wants to do for her, and others sharing their own confusion and feelings.

The video features six reasons why Daniel Mackler left his job as a psychotherapist, including a chaotic mental health system, pressure to make money, burnout, lack of support from colleagues, overwhelming responsibilities, and an interest in other things.